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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa10d935ccad73aa59ae3269b182ab745a9cf318e5136d7ec7ee6c6d096b5b05' 
  AND token = 'FrQFA0wQ2O9juySSXsbAn4Pd6wOSDkyysjDY0ql2mss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}