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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '547a649319db233a57598bb1570bb30919ac21a2a2b4a58c49c9c2c7d9867d63' 
  AND token = 'Qo4W4IlnvxKOb1VLd7yNXhzPQorvRTuMgUr1awgeEu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}