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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a881bded7f2d061f51fe9c11ba4b5c6e91927a2f097aff055c66d3f68ca7ba7' 
  AND token = 'LoDGrqY2COP33oZOVnNO6hoIzYVJyePN2M5a68L00Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}