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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20545fb7ddaf8335ca4a2b9ac4e2a120b4172c01e1e613e81f7cb691cfc81197' 
  AND token = 'S1L8KLhtRqH7JrS5v7u6CAwyQXZT/RuaA6akNVCg0Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}