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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b780fed4621d9490efc3b385b190d1827f8658c0ed6821369a85b0ab6836c9d3' 
  AND token = 'k9Jw9BzJxr5rhd2unYLNcICmjXS2Um0nb+vBXMzw1uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}