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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce828321c6ea1c29bb12f42cf2775f40bc6a1845813e05c52e68249cec597b3' 
  AND token = 'UkEmfgYOq0tXImCSHhPWZcRMQ5hd28jFVxRc9grYToM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}