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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac9885be67f91ab36cb78c9f46559c73873e3ca6b394b6b0c2759efece8ece7c' 
  AND token = 'K1DbAJC9ai4/lXWz5tSolxtoTx1sOf+yLC8FKKUdnXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}