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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af8af59958470c839c91bde3a23423e6a1b74ede242669daf53644c00be3b33' 
  AND token = 'v3td/d2N5lrftxVu/xKnEJASiqvr6pcG5rcKx6KwSdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}