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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb39f729af57d871ac2591cc0335b4abfd6750edfe0608dab1aa89bedae3443c' 
  AND token = 'YNaIXouTEqJJSVki/BI1xaD+cGFZFZHQ072XMf+oGgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}