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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380c8ac366dccf390b54169179ccb3d7e239b3e387177da9c0003333b985cd43' 
  AND token = 'jChIB86qfixsDm4X9gJl4X+aOCtVNUOQrwxfEoAmY1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}