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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59018b7764b83dddc153c8e6a0b60d10ec88c6a042ad36ebc3cd53e10170fa3d' 
  AND token = 'SLI4nMFw0ZKhxA6YFWXOBeWRzyQ4aXPL1aXYB6yKGE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}