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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e213252cdf047021345a04a04e4867568fc162cbc747ae387e115b4ad77cba' 
  AND token = 'rSbgLaUSELBtdlUSAFVvgv+f7zHHHpSGiXToMDqDYiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}