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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e51aea6b28554b3e06448959eb254f5f649402e529687d979f56b2753021e56' 
  AND token = 's//32i7E9lzYuJ7fDLh59povVpC0QCaBlm4dwIPzlfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}