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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07d58024f6374a61de91e820684b21d4be96e2df2a43ee03eb76d3fe27d07f17' 
  AND token = 'gB7KsO3kd+UrM1L9uZyOK+0+rVK+DGD4soEf/HC8dfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}