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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b292afbc287f7f2acd2e6fdb14da5c5ae8c5c0937bbaf4db8ff88a261725a8c' 
  AND token = 'TB/BlG3qHE//BaUbSsYXf7m3QfTjH6hK/MXzAmpEFWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}