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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1de441f2233fe8aa0e537dee3337a6e1cfd4baca34adfe40cd462d061068c74' 
  AND token = 'faxD3P6CW+Vl3UxxwIVHg5D/7weLN5VxIPHJ8JzxCb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}