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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca3c66280d6415ea786b471e5a1ef5c5a17df7da1082b51914e6816ed7eb97c3' 
  AND token = 'Uc/UPqjW8MdLPm7uUQGN8q2QkxqjXERqj8QhPiSi5iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}