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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd272aae326f83d6a899cad34fb8c465fea9f7a56c307d17b8d9a4aa395adbc99' 
  AND token = 'JyTw5w0Rzb26Df4PINdaOV6q0Wm7pcyV+QUb3AXpByQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}