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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af533280862df0638e87d016173c3cc6640d9601003987e5c30961019a64cb0f' 
  AND token = '5QNzgklRKc22kTwXJKpcFb7VK7NOmGQ4oQAd8DI2GRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}