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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47946a18045c21b28c282f6e6834899ca25cbdc8e28e1382bd4a5a8ce6faca60' 
  AND token = 'KQFZO3gCz+HX/vnf2eaLhvIap85gtUWKc7EVhXAEd1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}