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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f447d64a99da188e97f52f33a60df6371d4228f8fd2d9a9f4b7ea360f3b6f4f8' 
  AND token = 'RVUxKtcJR9RQxxiyPBt8RkrlUlDbvOP6+dV1HvUDVvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}