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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '236f29e3d2f806643c2e486e54a9d90627b45b61696081b6abd4c43172093aee' 
  AND token = 'TTbWytmRI6HS2KHpZbsikZCbgh4PT2utslGfBki3JKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}