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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6fd93de87f7ffd3dbd9dee681474799ed2dd48b5c4002b84df5b2f16007414e' 
  AND token = 'uACYFMm5Grh+fd9e+Ka1r+cshczZS4FbfmZLexYzHyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}