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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3753f489339fe54aee853bef068581d079017ab9ddb985b58e687b4975a74eac' 
  AND token = 'EvDjT8QWyWj9rYkz8+oE3gsr2IHHnlRTb0ceTOBxSF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}