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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81685076103172f4e36ba22a7d17cf5afe746b236eb4d9c41b43bfb6cb3e253a' 
  AND token = '5TDg8buZ6S2kxaaax0HQTcsYtBP6Zzgb+KuoipnfUuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}