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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b94e2553e9964c5a3050c11a747176a03b7d5f92c8285a4c692cc283a498891' 
  AND token = 'YiQsoa48OZaNALBUP51aAYS9d1/6h2Ebt10z0iJBN5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}