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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a46c29ea96d0f1663905d8c699833e22eecf62d14c1561adc66bb0a20345eb3' 
  AND token = 'PepSGKPRCR05fB/Iu3Zino+oJ9RNf12OKye99f55ZOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}