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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b355686e43c067000f2a4cbe2cac11ba89ae0de5ecfc1d484615334e1118387' 
  AND token = '+565K631A8eFsp2kRgIrHleVSNII05beSInXtTKOmO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}