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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5e838952638c14997247a51be7b733223651b72b5515891d40a94a13a57c34' 
  AND token = 'DFEDCOQ1SkyIXXm4aUW3HR9JHGl1cJpoMCdwn2nNhXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}