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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dba25f49ac2dbe1a86477c1bca2d133699296442958b574501e97e17f424dab' 
  AND token = 'qAf6bNxxhZ5zpOBuAIOTIRyWW9Bu64YftAC3b7uPqBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}