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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c8d5a3a5a6236b883f77f2501310358c9320ce8df80f521453a4eb1ceb8cff8' 
  AND token = 'wjmJ1G+BPAP60qmqTF4ItJ6lJv1eY8zu4GLZR2nD550=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}