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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6406872f851d366f55d4440b58ad64cdf566c096ec0b9b736afb1ed06e18c6d' 
  AND token = 'IrPosMvY2QH8lwTz96wEsxUOjsuw5j9lRODP9BO/Ib4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}