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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b804cca40fe84d834352ac2131664048fb689cf079a95a3e3568c6cc165971ab' 
  AND token = 'VMIoQUR6u8OOlt3bqadWnx+2v2sQCv9MBFSWTKB5kF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}