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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd7e0d8c57d879caf208132c12c9c2657bde52c0404d737f68c0382dd649464' 
  AND token = 'Ncjs83JRUZlbVf+bh2Kl94rD/+30RzBOhnS+S5rbwuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}