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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a4fa284b68e36b747c8392b10dce98a3b1048da27f24ca1eaf649e47053fc2' 
  AND token = 'Un/XBUpscUmW77rq0A5DEmZ09Dhv5JRDeIhnmtI4SPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}