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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c93e4a83a94dfde750461dc066c0bb553d39f1be2069e0fba714ebb886a80f6' 
  AND token = 'qOArfts4fy6PZy6+2+6/2p2j4HvJdwGW1KlMpwZJqbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}