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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3c4ed1ef0105cd706438b4817930e942abe3bd256058e9aa1bdc48f87fcd73' 
  AND token = 'd1bpT6QGtyoGc4SiV/yBcihp15kGDZddEPcppZmus4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}