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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3946e1e27984cd7c2518cfced95f154402ecbaf82cf0ad4f7d689d6ab0460843' 
  AND token = 'k9/ot+827ESF2huyZ3WX+hSNKBnypnPA1uo9Nh6+yd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}