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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '838ed75067915c40b020d33d7804eca69127fd2bf1cb1e720951b41159a553a9' 
  AND token = 'TAtyfE40xBe6Y0Pf7fLQI5JCRPVF3tkynKiN6+ADtnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}