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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8208098abe1efb6ba56fff7e22281ed12a73b23f2b205b90cf1619ab4ac393' 
  AND token = 'S/kESO2e2ktfzexmV/n5eZhpAot/OgoNebTGEyoESZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}