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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3854730bb06ba8d2c37889084b6dcd748c5735fd2a0ac2c6d3ffb6370fc34c15' 
  AND token = 'vjEQOBWLoTsnwSr4Wml/JmlYlPJgUS8xwSJoNvHJrvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}