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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e77e8e2aea71b113c765826184e18dcde301ba3f8a4f17f0a9fbb6e7f9b3268f' 
  AND token = 'ibfxXzY+hNtbwX2pGZLWWG7XN48N4iWefd/fcmvDfhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}