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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28aef50346b124df575c3bf90fb2cf67c1794d253a7d6f68a9bcc6cda9de06be' 
  AND token = 'vaXielvIJq+CRQDCK3qOA6aKlDHL7Kkd0TVIpIqSgCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}