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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0153280c4b3962c96a65a86e799b3f493c1071450d9c2bc8ebd952d9ec5a3e26' 
  AND token = 'Boe0RIuPmBJyA1htZp6sJqs4ZV/mU8CSAQx4rrp+4w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}