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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583ddb3dc159900e2e0d2e98fa79d12fc67050ed51fe46a4fd72def6ce2a5fc6' 
  AND token = 'TmeStPwUykSFne7tGwhWmdM+4xwkW92tawTLkukUGNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}