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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce60b358c7aaf4723b4e982ef32473add29c4cffaec0d3bb5806230279b96f61' 
  AND token = 'fl9+TXWPw+7/Tl9b2vaUF8YfbqNrrMLmWE4hJ0SVVho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}