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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216000411c00cd234d27d5c6388288b49137d26351a8f2a7d07e1a2193cb0e32' 
  AND token = 'Lgb43aalS9+rOhHRiEi1aD1SA2Da13WTaUGQI4JIOyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}