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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded173d29b93380ecf25f78cb6c6daac0df2539f4f83d4bb6c72d878b91da45a' 
  AND token = 'zCOFEu7cbFLDVroeeNFEIjX60Jt5bse3xin9/HIoj9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}