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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb49ea003654bfc5864ba069016f9155410c2e2b1ccbc0d00f4f39c2b2ab548' 
  AND token = 'berwCFl9EzUcySiWQQXHhW819/ze3gvOKm8EHY2K5VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}