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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1294b33c8b2403f633567f476e6628865b1164a2f1dcd471487fe82118ce897' 
  AND token = 'i7Vjbtm35k2Q6r7yfqEeZS/tf8AtKnlzKqPfH7puQXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}